Breathe Biologics

is advancing a patented clinically validated regenerative immunomodulatory platform designed to address severe pulmonary disease through immune modulation, tissue repair, and scalable cell therapy manufacturing—creating a potential foundation for the future of regenerative pulmonary medicine

COPD is a consistently progressive, ultimately fatal disease.

15.7

million Americans (6.4%) reported that they have been diagnosed with COPD

50%

of adults with low pulmonary function were not aware that they had COPD

3.23

million deaths worldwide in 2019. COPD is the third leading cause of death worldwide

90%

of COPD deaths in those under 70 years of age occur in low- and middle-income countries

7th

leading cause of poor health worldwide is COPD

70%

of COPD is smoking related in high-income countries

To determine safety and efficacy of intravenously administered allogeneic JadiCell umbilical cord tissue derived mesenchymal stem cells in patients with moderate-to-severe COPD.

The overall objective of this protocol is to confirm safety and determine effectiveness of “JadiCell” Umbilical Cord Mesenchymal Stem Cell (UC-MSC) infusions in subjects with ARDS.